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Cardiac myosin binding protein-C: redefining its structure and function

Mutations of cardiac myosin binding protein-C (cMyBP-C) are inherited by an estimated 60 million people worldwide, and the protein is the target of several kinases. Recent evidence further suggests that cMyBP-C mutations alter Ca(2+) transients, leading to electrophysiological dysfunction. Thus, whi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sadayappan, Sakthivel, de Tombe, Pieter P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer-Verlag 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374655/
https://ncbi.nlm.nih.gov/pubmed/22707987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12551-012-0067-x
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