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Pathogenic properties of the N-terminal region of cardiac myosin binding protein-C in vitro
Cardiac myosin binding protein-C (cMyBP-C) plays a role in sarcomeric structure and stability, as well as modulating heart muscle contraction. The 150 kDa full-length (FL) cMyBP-C has been shown to undergo proteolytic cleavage during ischemia–reperfusion injury, producing an N-terminal 40 kDa fragme...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3368277/ https://ncbi.nlm.nih.gov/pubmed/22527638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10974-012-9292-y |
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