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Bayesian design using adult data to augment pediatric trials
BACKGROUND: It can be difficult to conduct pediatric clinical trials because there is often a low incidence of the disease in children, making accrual slow or infeasible. In addition, low mortality and morbidity in this population make it impractical to achieve adequate power. In this case, the only...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3374646/ https://ncbi.nlm.nih.gov/pubmed/19667026 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774509339238 |
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