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Endocytic control of growth factor signalling: multivesicular bodies as signalling organelles
Signal transduction and endocytosis are intertwined processes. The internalization of ligand-activated receptors by endocytosis has classically been thought to attenuate signals by targeting receptors for degradation in lysosomes, but it can also maintain signals in early signalling endosomes. In bo...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3374592/ https://ncbi.nlm.nih.gov/pubmed/22108513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3244 |
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