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Endocytic control of growth factor signalling: multivesicular bodies as signalling organelles

Signal transduction and endocytosis are intertwined processes. The internalization of ligand-activated receptors by endocytosis has classically been thought to attenuate signals by targeting receptors for degradation in lysosomes, but it can also maintain signals in early signalling endosomes. In bo...

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Detalhes bibliográficos
Main Authors: Dobrowolski, Radek, De Robertis, Edward M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374592/
https://ncbi.nlm.nih.gov/pubmed/22108513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3244
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