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Crystallization and preliminary crystallographic study of a trypsin-resistant catalytic domain of human calcineurin
Calcineurin, a Ca(2+)/calmodulin-dependent serine/threonine protein phosphatase, plays a key role in a number of cellular pathways, including T-cell activation, and is an important molecular target of the immunosuppressive drugs cyclosporin A and FK506. To understand the structural basis underlying...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
International Union of Crystallography
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3374516/ https://ncbi.nlm.nih.gov/pubmed/22691791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309112007890 |
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