A High-Throughput Scintillation Proximity-Based Assay for Human DNA Ligase IV

Ionizing radiation (IR) and certain chemotherapeutic drugs are designed to generate cytotoxic DNA double-strand breaks (DSBs) in cancer cells. Inhibition of the major DSB repair pathway, nonhomologous end joining (NHEJ), will enhance the cytotoxicity of these agents. Screening for inhibitors of the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Tseng, Hui-Min, Shum, David, Bhinder, Bhavneet, Escobar, Sindy, Veomett, Nicholas J., Tomkinson, Alan E., Gin, David Y., Djaballah, Hakim, Scheinberg, David A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Mary Ann Liebert, Inc. 2012
Pynciau:
Original Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374410/
https://ncbi.nlm.nih.gov/pubmed/22192310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2011.0404
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