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Human chondrogenic paraxial mesoderm, directed specification and prospective isolation from pluripotent stem cells

Directed specification and prospective isolation of chondrogenic paraxial mesoderm progeny from human pluripotent stem (PS) cells have not yet been achieved. Here we report the successful generation of KDR(−)PDGFRα(+) progeny expressing paraxial mesoderm genes and the mesendoderm reporter MIXL1-GFP...

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Main Authors: Umeda, Katsutsugu, Zhao, Jiangang, Simmons, Paul, Stanley, Edouard, Elefanty, Andrew, Nakayama, Naoki
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3374161/
https://ncbi.nlm.nih.gov/pubmed/22701159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00455
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