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Rickettsiae Induce Microvascular Hyperpermeability via Phosphorylation of VE-Cadherins: Evidence from Atomic Force Microscopy and Biochemical Studies
The most prominent pathophysiological effect of spotted fever group (SFG) rickettsial infection of microvascular endothelial cells (ECs) is an enhanced vascular permeability, promoting vasogenic cerebral edema and non-cardiogenic pulmonary edema, which are responsible for most of the morbidity and m...
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Glavni autori: | , , , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
Public Library of Science
2012
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3373609/ https://ncbi.nlm.nih.gov/pubmed/22720111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001699 |
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