Rickettsiae Induce Microvascular Hyperpermeability via Phosphorylation of VE-Cadherins: Evidence from Atomic Force Microscopy and Biochemical Studies

The most prominent pathophysiological effect of spotted fever group (SFG) rickettsial infection of microvascular endothelial cells (ECs) is an enhanced vascular permeability, promoting vasogenic cerebral edema and non-cardiogenic pulmonary edema, which are responsible for most of the morbidity and m...

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Hlavní autoři: Gong, Bin, Ma, Liang, Liu, Yan, Gong, Qinyu, Shelite, Thomas, Bouyer, Donald, Boor, Paul J., Lee, Yong Sun, Oberhauser, Andres
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3373609/
https://ncbi.nlm.nih.gov/pubmed/22720111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001699
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