Rickettsiae Induce Microvascular Hyperpermeability via Phosphorylation of VE-Cadherins: Evidence from Atomic Force Microscopy and Biochemical Studies

The most prominent pathophysiological effect of spotted fever group (SFG) rickettsial infection of microvascular endothelial cells (ECs) is an enhanced vascular permeability, promoting vasogenic cerebral edema and non-cardiogenic pulmonary edema, which are responsible for most of the morbidity and m...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Gong, Bin, Ma, Liang, Liu, Yan, Gong, Qinyu, Shelite, Thomas, Bouyer, Donald, Boor, Paul J., Lee, Yong Sun, Oberhauser, Andres
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3373609/
https://ncbi.nlm.nih.gov/pubmed/22720111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001699
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