Загрузка...
The IFT-A complex regulates Shh signaling through cilia structure and membrane protein trafficking
Two intraflagellar transport (IFT) complexes, IFT-A and IFT-B, build and maintain primary cilia and are required for activity of the Sonic hedgehog (Shh) pathway. A weak allele of the IFT-A gene, Ift144, caused subtle defects in cilia structure and ectopic activation of the Shh pathway. In contrast,...
Сохранить в:
| Главные авторы: | , , , , , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Rockefeller University Press
2012
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3373400/ https://ncbi.nlm.nih.gov/pubmed/22689656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201110049 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|