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Canalization of the evolutionary trajectory of the human influenza virus
BACKGROUND: Since its emergence in 1968, influenza A (H3N2) has evolved extensively in genotype and antigenic phenotype. However, despite strong pressure to evolve away from human immunity and to diversify in antigenic phenotype, H3N2 influenza shows paradoxically limited genetic and antigenic diver...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3373370/ https://ncbi.nlm.nih.gov/pubmed/22546494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-10-38 |
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