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Effect of Thymine Glycol on Transcription Elongation by T7 RNA Polymerase and Mammalian RNA Polymerase II

Thymine glycols are formed in DNA by exposure to ionizing radiation or oxidative stress. Although these lesions are repaired by the base excision repair pathway, they have been shown also to be subject to transcription-coupled repair. A current model for transcription-coupled repair proposes that RN...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tornaletti, Silvia, Maeda, Lauren S., Lloyd, Daniel R., Reines, Daniel, Hanawalt, Philip C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3373304/
https://ncbi.nlm.nih.gov/pubmed/11571287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M105282200
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