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Mipomersen: evidence-based review of its potential in the treatment of homozygous and severe heterozygous familial hypercholesterolemia

Familial hypercholesterolemia (FH) is an autosomal-dominant inherited disease with a prevalence of one in 500 (heterozygous) to one in 1,000,000 (homozygous). Mutations of the low-density lipoprotein (LDL) receptor gene, the apolipoprotein B100 gene, or the PCSK9 gene may be responsible for the dise...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखक: Parhofer, Klaus G
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Dove Medical Press 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3373191/
https://ncbi.nlm.nih.gov/pubmed/22701100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CE.S25239
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