Skin effector memory T cells do not recirculate and provide immune protection in alemtuzumab-treated CTCL patients

CTCL is a cancer of skin homing T cells with variants that include leukemic CTCL (L-CTCL), a malignancy of central memory T cells (T(CM)), and mycosis fungoides (MF), a malignancy of skin resident effector memory T cells (T(EM)). We report that low-dose alemtuzumab (αCD52) effectively treated patien...

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Main Authors: Clark, Rachael A., Watanabe, Rei, Teague, Jessica E., Schlapbach, Christoph, Tawa, Marianne C., Adams, Natalie, Dorosario, Andrew A., Chaney, Keri S., Cutler, Corey S., LeBoeuf, Nicole R., Carter, Joi B., Fisher, David C., Kupper, Thomas S.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3373186/
https://ncbi.nlm.nih.gov/pubmed/22261031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3003008
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