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The Effect of Adenovirus-Mediated Gene Expression of FHIT in Small Cell Lung Cancer Cells

The candidate tumor suppressor fragile histidine traid (FHIT) is frequently inactivated in small cell lung cancer (SCLC). Mutations in the p53 gene also occur in the majority of SCLC leading to the accumulation of the mutant protein. Here we evaluated the effect of FHIT gene therapy alone or in comb...

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Bibliographic Details
Main Authors: Zandi, Roza, Xu, Kai, Poulsen, Hans S., Roth, Jack A., Ji, Lin
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372907/
https://ncbi.nlm.nih.gov/pubmed/22085272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/07357907.2011.626475
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