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Induction of Apoptosis by Tumor Suppressor FHIT via Death Receptor Signaling Pathway in Human Lung Cancer Cells

FHIT is a novel tumor suppressor gene located at human chromosome 3p14.2. Restoration of wild-type FHIT in 3p14.2-deficient human lung cancer cells inhibits cell growth and induces apoptosis. In this study, we analyzed potential upstream/downstream molecular targets of the FHIT protein and found tha...

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Detalles Bibliográficos
Main Authors: Deng, Wu-Guo, Nishizaki, Masahiko, Fang, Bingliang, Roth, Jack A., Ji, Lin
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1934611/
https://ncbi.nlm.nih.gov/pubmed/17328863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.02.067
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