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Reduction in Tcf7l2 Expression Decreases Diabetic Susceptibility in Mice
Objective: The WNT signaling pathway effector gene TCF7L2 has been associated with an increased risk of type 2 diabetes. However, it remains unclear how this gene affects diabetic pathogenesis. The goal of this study was to investigate the effects of Tcf7l2 haploinsufficiency on metabolic phenotypes...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Ivyspring International Publisher
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3372883/ https://ncbi.nlm.nih.gov/pubmed/22719219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.4568 |
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