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Reduction in Tcf7l2 Expression Decreases Diabetic Susceptibility in Mice

Objective: The WNT signaling pathway effector gene TCF7L2 has been associated with an increased risk of type 2 diabetes. However, it remains unclear how this gene affects diabetic pathogenesis. The goal of this study was to investigate the effects of Tcf7l2 haploinsufficiency on metabolic phenotypes...

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Detalhes bibliográficos
Main Authors: Yang, Hyekyung, Li, Qing, Lee, Jong-Hwan, Shu, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372883/
https://ncbi.nlm.nih.gov/pubmed/22719219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.4568
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