Structural MRI detects progressive regional brain atrophy and neuroprotective effects in N171-82Q Huntington's disease mouse model

Huntington's disease (HD) displays progressive striatal atrophy that occurs long before the onset of clinical motor symptoms. As there is no treatment for the disease once overt symptoms appear, it has been suggested that neuroprotective therapy given during this presymptomatic period might slo...

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Autori principali: Cheng, Yong, Peng, Qi, Hou, Zhipeng, Aggarwal, Manisha, Zhang, Jiangyang, Mori, Susumu, Ross, Christopher A., Duan, Wenzhen
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372851/
https://ncbi.nlm.nih.gov/pubmed/21320608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2011.02.022
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