Cannabinoid CB(2) receptors modulate ERK-1/2 kinase signalling and NO release in microglial cells stimulated with bacterial lipopolysaccharide

BACKGROUND AND PURPOSE: Cannabinoid (CB) receptor agonists have potential utility as anti-inflammatory drugs in chronic immune inflammatory diseases. In the present study, we characterized the signal transduction pathways affected by CB(2) receptors in quiescent and lipopolysaccharide (LPS)-stimulat...

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Detalhes bibliográficos
Main Authors: Merighi, Stefania, Gessi, Stefania, Varani, Katia, Simioni, Carolina, Fazzi, Debora, Mirandola, Prisco, Borea, Pier Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372829/
https://ncbi.nlm.nih.gov/pubmed/21951063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01673.x
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