A(3) Adenosine Receptors Modulate Hypoxia-Inducible Factor-1α Expression in Human A375 Melanoma Cells

Hypoxia-inducible factor-1 (HIF-1) is a key regulator of genes crucial to many aspects of cancer biology. The purine nucleoside, adenosine, accumulates within many tissues under hypoxic conditions, including that of tumors. Because the levels of both HIF-1 and adenosine are elevated within the hypox...

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Bibliografiska uppgifter
Huvudupphovsmän: Merighi, Stefania, Benini, Annalisa, Mirandola, Prisco, Gessi, Stefania, Varani, Katia, Leung, Edward, MacLennan, Stephen, Baraldi, Pier Giovanni, Borea, Pier Andrea
Materialtyp: Artigo
Språk:Inglês
Publicerad: Neoplasia Press Inc. 2005
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1502026/
https://ncbi.nlm.nih.gov/pubmed/16242072
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