Phosphodiesterase Inhibitor Improves Renal Tubulointerstitial Hypoxia of the Diabetic Rat Kidney

BACKGROUND/AIMS: Renal hypoxia is involved in the pathogenesis of diabetic nephropathy. Pentoxifyllin (PTX), a nonselective phosphodiesterase inhibitor, is used to attenuate peripheral vascular diseases. To determine whether PTX can improve renal hypoxia, we investigated its effect in the streptozoc...

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Autors principals: Sun, Hui-Kyoung, Lee, Yun Mi, Han, Kum Hyun, Kim, Han-Seong, Ahn, Seon-Ho, Han, Sang-Youb
Format: Artigo
Idioma:Inglês
Publicat: The Korean Association of Internal Medicine 2012
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372800/
https://ncbi.nlm.nih.gov/pubmed/22707888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3904/kjim.2012.27.2.163
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