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Natural killer T cells suppress zymosan A-mediated granuloma formation in the liver by modulating interferon-γ and interleukin-10

Wild-type (WT) and CD1d(−/−) [without natural killer (NK) T cells] mice were treated with zymosan A to induce granuloma formation in the liver. Increased granuloma formation was seen in NKT-less mice on days 7 and 14 after administration. WT mice showed limited granuloma formation, and zymosan A eve...

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Detalhes bibliográficos
Main Authors: Kobayashi, Takahiro, Kawamura, Hiroki, Kanda, Yasuhiro, Matsumoto, Hiroaki, Saito, Suguru, Takeda, Kazuyoshi, Kawamura, Toshihiko, Abo, Toru
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372760/
https://ncbi.nlm.nih.gov/pubmed/22268994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2012.03562.x
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