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Coincidence of autoantibody production with the activation of natural killer T cells in α-galactosylceramide-mediated hepatic injury

Natural killer T (NKT) cells are known to be specifically activated by α-galactosylceramide (α-GalCer) via their interaction with CD1d. At that time, NKT cells mediate autoreactivity and eventually induce hepatic injury. As these immune responses resemble acute autoimmune hepatitis, it was examined...

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Detalhes bibliográficos
Main Authors: Matsumoto, Hiroaki, Kawamura, Toshihiko, Kobayashi, Takahiro, Kanda, Yasuhiro, Kawamura, Hiroki, Abo, Toru
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088964/
https://ncbi.nlm.nih.gov/pubmed/21320121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2011.03405.x
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