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T-cell receptor affinity in thymic development

Understanding the thymic processes that support the generation of functionally competent and self-tolerant lymphocytes requires dissection of the T-cell receptor (TCR) response to ligands of different affinities. In spatially segregated regions of the thymus, with unique expression of proteases and...

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Autors principals: Moran, Amy E, Hogquist, Kristin A
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372742/
https://ncbi.nlm.nih.gov/pubmed/22182461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2011.03547.x
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