Non-bronchodilating mechanisms of tiotropium prevent airway hyperreactivity in a guinea-pig model of allergic asthma

BACKGROUND AND PURPOSE: Asthma is characterized by reversible bronchoconstriction and airway hyperreactivity. Although M(3) muscarinic receptors mediate bronchoconstriction, non-selective muscarinic receptor antagonists are not currently recommended for chronic control of asthma. We tested whether s...

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Autores principales: Buels, KS, Jacoby, DB, Fryer, AD
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Publishing Ltd 2012
Materias:
Research Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372733/
https://ncbi.nlm.nih.gov/pubmed/21871018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01632.x
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