EGFR Somatic Mutations in Lung Tumors: Radon Exposure and Passive-smoking in Former- and Never-smoking U.S. Women

BACKGROUND: Lung cancer patients with mutations in EGFR tyrosine kinase have improved prognosis when treated with EGFR inhibitors. We hypothesized that EGFR mutations may be related to residential radon or passive tobacco smoke. METHODS: This hypothesis was investigated by analyzing EGFR mutations i...

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Päätekijät: Taga, Masataka, Mechanic, Leah E., Hagiwara, Nobutoshi, Vähäkangas, Kirsi H., Bennett, William P., Alavanja, Michael C. R., Welsh, Judith A., Khan, Mohammed A., Lee, Adam, Diasio, Robert, Edell, Eric, Bungum, Aaron, Jang, Jin Sung, Yang, Ping, Jen, Jin, Harris, Curtis C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372599/
https://ncbi.nlm.nih.gov/pubmed/22523180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-12-0166
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