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EGFR Somatic Mutations in Lung Tumors: Radon Exposure and Passive-smoking in Former- and Never-smoking U.S. Women

BACKGROUND: Lung cancer patients with mutations in EGFR tyrosine kinase have improved prognosis when treated with EGFR inhibitors. We hypothesized that EGFR mutations may be related to residential radon or passive tobacco smoke. METHODS: This hypothesis was investigated by analyzing EGFR mutations i...

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Detalhes bibliográficos
Main Authors: Taga, Masataka, Mechanic, Leah E., Hagiwara, Nobutoshi, Vähäkangas, Kirsi H., Bennett, William P., Alavanja, Michael C. R., Welsh, Judith A., Khan, Mohammed A., Lee, Adam, Diasio, Robert, Edell, Eric, Bungum, Aaron, Jang, Jin Sung, Yang, Ping, Jen, Jin, Harris, Curtis C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372599/
https://ncbi.nlm.nih.gov/pubmed/22523180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-12-0166
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