Antioxidant Protects against Increases in Low Molecular Weight Hyaluronan and Inflammation in Asphyxiated Newborn Pigs Resuscitated with 100% Oxygen

BACKGROUND: Newborn resuscitation with 100% oxygen is associated with oxidative-nitrative stresses and inflammation. The mechanisms are unclear. Hyaluronan (HA) is fragmented to low molecular weight (LMW) by oxidative-nitrative stresses and can promote inflammation. We examined the effects of 100% o...

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Main Authors: Østerholt, Helene C. D., Dannevig, Ingrid, Wyckoff, Myra H., Liao, Jie, Akgul, Yucel, Ramgopal, Mrithyunjay, Mija, Dan S., Cheong, Naeun, Longoria, Christopher, Mahendroo, Mala, Nakstad, Britt, Saugstad, Ola D., Savani, Rashmin C.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372475/
https://ncbi.nlm.nih.gov/pubmed/22701723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038839
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