Ezrin phosphorylation on tyrosine 477 regulates invasion and metastasis of breast cancer cells

BACKGROUND: The membrane cytoskeletal crosslinker, ezrin, a member of the ERM family of proteins, is frequently over-expressed in human breast cancers, and is required for motility and invasion of epithelial cells. Our group previously showed that ezrin acts co-operatively with the non-receptor tyro...

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Bibliographic Details
Main Authors: Mak, Hannah, Naba, Alexandra, Varma, Sonal, Schick, Colleen, Day, Andrew, SenGupta, Sandip K, Arpin, Monique, Elliott, Bruce E
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372425/
https://ncbi.nlm.nih.gov/pubmed/22397367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-82
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