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Large-scale experimental studies show unexpected amino acid effects on protein expression and solubility in vivo in E. coli

The biochemical and physical factors controlling protein expression level and solubility in vivo remain incompletely characterized. To gain insight into the primary sequence features influencing these outcomes, we performed statistical analyses of results from the high-throughput protein-production...

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Bibliografiske detaljer
Main Authors: Price, W Nicholson, Handelman, Samuel K, Everett, John K, Tong, Saichiu N, Bracic, Ana, Luff, Jon D, Naumov, Victor, Acton, Thomas, Manor, Philip, Xiao, Rong, Rost, Burkhard, Montelione, Gaetano T, Hunt, John F
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372292/
https://ncbi.nlm.nih.gov/pubmed/22587847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2042-5783-1-6
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