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Understanding the physical properties controlling protein crystallization based on analysis of large-scale experimental data

Crystallization has proven to be the most significant bottleneck to high-throughput protein structure determination using diffraction methods. We have used the large-scale, systematically generated experimental results of the Northeast Structural Genomics Consortium to characterize the biophysical p...

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主要な著者: Price, W. Nicholson, Chen, Yang, Handelman, Samuel K., Neely, Helen, Manor, Philip, Karlin, Richard, Nair, Rajesh, Liu, Jinfeng, Baran, Michael, Everett, John, Tong, Saichiu N., Forouhar, Farhad, Swaminathan, Swarup S., Acton, Thomas, Xiao, Rong, Luft, Joseph R., Lauricella, Angela, DeTitta, George T., Rost, Burkhard, Montelione, Gaetano T., Hunt, John F.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746436/
https://ncbi.nlm.nih.gov/pubmed/19079241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1514
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