Understanding the physical properties controlling protein crystallization based on analysis of large-scale experimental data

Crystallization has proven to be the most significant bottleneck to high-throughput protein structure determination using diffraction methods. We have used the large-scale, systematically generated experimental results of the Northeast Structural Genomics Consortium to characterize the biophysical p...

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Main Authors: Price, W. Nicholson, Chen, Yang, Handelman, Samuel K., Neely, Helen, Manor, Philip, Karlin, Richard, Nair, Rajesh, Liu, Jinfeng, Baran, Michael, Everett, John, Tong, Saichiu N., Forouhar, Farhad, Swaminathan, Swarup S., Acton, Thomas, Xiao, Rong, Luft, Joseph R., Lauricella, Angela, DeTitta, George T., Rost, Burkhard, Montelione, Gaetano T., Hunt, John F.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746436/
https://ncbi.nlm.nih.gov/pubmed/19079241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1514
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