Recombinant Monoclonal Antibody Recognizes a Unique Epitope on Varicella-Zoster Virus Immediate-Early 63 Protein

We previously constructed a recombinant monoclonal antibody (rec-MAb 63P4) that detects immediate-early protein IE63 encoded by varicella-zoster virus (VZV) in the cytoplasm of productively infected cells. Here, we used ORF63 truncation mutants to map the rec-MAb 63P4 binding epitope to amino acids...

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Detalhes bibliográficos
Main Authors: Mueller, Niklaus H., Bos, Nathan L., Seitz, Scott, Wellish, Mary, Mahalingam, Ravi, Gilden, Don, Cohrs, Randall J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Structure and Assembly
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372203/
https://ncbi.nlm.nih.gov/pubmed/22438547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06814-11
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