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Varicella-Zoster Virus Open Reading Frame 48 Encodes an Active Nuclease

Based on a DNA sequence and relative genomic position similar to those other herpesviruses, varicella-zoster virus (VZV) open reading frame 48 (ORF48) is predicted to encode an alkaline nuclease. Here we report the cloning, expression, purification, and characterization of recombinant VZV ORF48 prot...

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Detalhes bibliográficos
Main Authors: Mueller, Niklaus H., Gilden, Don, Cohrs, Randall J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807315/
https://ncbi.nlm.nih.gov/pubmed/23966396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01879-13
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