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Evidence for ACE2-Utilizing Coronaviruses (CoVs) Related to Severe Acute Respiratory Syndrome CoV in Bats

In 2002, severe acute respiratory syndrome (SARS)-coronavirus (CoV) appeared as a novel human virus with high similarity to bat coronaviruses. However, while SARS-CoV uses the human angiotensin-converting enzyme 2 (ACE2) receptor for cellular entry, no coronavirus isolated from bats appears to use A...

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Detalhes bibliográficos
Main Authors: Demogines, Ann, Farzan, Michael, Sawyer, Sara L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3372174/
https://ncbi.nlm.nih.gov/pubmed/22438550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00311-12
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