Two-Way Antigenic Cross-Reactivity between Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and Group 1 Animal CoVs Is Mediated through an Antigenic Site in the N-Terminal Region of the SARS-CoV Nucleoprotein

In 2002, severe acute respiratory syndrome-associated coronavirus (SARS-CoV) emerged in humans, causing a global epidemic. By phylogenetic analysis, SARS-CoV is distinct from known CoVs and most closely related to group 2 CoVs. However, no antigenic cross-reactivity between SARS-CoV and known CoVs w...

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Main Authors: Vlasova, Anastasia N., Zhang, Xinsheng, Hasoksuz, Mustafa, Nagesha, Hadya S., Haynes, Lia M., Fang, Ying, Lu, Shan, Saif, Linda J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2007
Fag:
Genetic Diversity and Evolution
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168854/
https://ncbi.nlm.nih.gov/pubmed/17913799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01169-07
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