MoRFpred, a computational tool for sequence-based prediction and characterization of short disorder-to-order transitioning binding regions in proteins

Motivation: Molecular recognition features (MoRFs) are short binding regions located within longer intrinsically disordered regions that bind to protein partners via disorder-to-order transitions. MoRFs are implicated in important processes including signaling and regulation. However, only a limited...

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Détails bibliographiques
Auteurs principaux: Disfani, Fatemeh Miri, Hsu, Wei-Lun, Mizianty, Marcin J., Oldfield, Christopher J., Xue, Bin, Dunker, A. Keith, Uversky, Vladimir N., Kurgan, Lukasz
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2012
Sujets:
Ismb 2012 Proceedings Papers Committee July 15 to July 19, 2012, Long Beach, Ca, Usa
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371841/
https://ncbi.nlm.nih.gov/pubmed/22689782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts209
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