Recognition models to predict DNA-binding specificities of homeodomain proteins

Motivation: Recognition models for protein-DNA interactions, which allow the prediction of specificity for a DNA-binding domain based only on its sequence or the alteration of specificity through rational design, have long been a goal of computational biology. There has been some progress in constru...

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Autori principali: Christensen, Ryan G., Enuameh, Metewo Selase, Noyes, Marcus B., Brodsky, Michael H., Wolfe, Scot A., Stormo, Gary D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2012
Soggetti:
Ismb 2012 Proceedings Papers Committee July 15 to July 19, 2012, Long Beach, Ca, Usa
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371834/
https://ncbi.nlm.nih.gov/pubmed/22689783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts202
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