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Double-Fold C-H Oxygenation of Arenes Using PyrDipSi: a General and Efficient Traceless/Modifiable Silicon-Tethered Directing Group

The efficient Pd-catalyzed double-fold C-H oxygenation of arenes into resorcinols using newly developed 2-pyrimidyldiisopropylsilyl (PyrDipSi) directing group is described. Its employment allows for a sequential introduction of OAc and OPiv groups in a one-pot manner to produce orthogonally protecte...

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Detalhes bibliográficos
Main Authors: Gulevich, Anton V., Melkonyan, Ferdinand S., Sarkar, Dhruba, Gevorgyan, Vladimir
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371766/
https://ncbi.nlm.nih.gov/pubmed/22414133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3010545
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