Unexpected multivalent display of proteins by temperature triggered self-assembly of elastin-like polypeptide block copolymers

We report herein the unexpected temperature triggered self-assembly of proteins fused to thermally responsive elastin-like polypeptides (ELPs) into spherical micelles. Six ELP block copolymers (ELP(BC)) with different hydrophilic and hydrophobic block lengths were genetically fused to two single dom...

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Autori principali: Hassouneh, Wafa, Fischer, Karl, MacEwan, Sarah R., Branscheid, Robert, Fu, Chuan Lawrence, Liu, Rihe, Schmidt, Manfred, Chilkoti, Ashutosh
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371654/
https://ncbi.nlm.nih.gov/pubmed/22515311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm300321n
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