Variants in CPT1A, FADS1, and FADS2 are Associated with Higher Levels of Estimated Plasma and Erythrocyte Delta-5 Desaturases in Alaskan Eskimos

The delta-5 and delta-6 desaturases (D5D and D6D), encoded by fatty acid desaturase 1 (FADS1) and 2 (FADS2) genes, respectively, are rate-limiting enzymes in the metabolism of ω-3 and ω-6 fatty acids. The objective of this study was to identify genes influencing variation in estimated D5D and D6D ac...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Voruganti, V. Saroja, Higgins, Paul B., Ebbesson, Sven O. E., Kennish, John, Göring, Harald H. H., Haack, Karin, Laston, Sandra, Drigalenko, Eugene, Wenger, Charlotte R., Harris, William S., Fabsitz, Richard R., Devereux, Richard B., MacCluer, Jean W., Curran, Joanne E., Carless, Melanie A., Johnson, Matthew P., Moses, Eric K., Blangero, John, Umans, Jason G., Howard, Barbara V., Cole, Shelley A., Comuzzie, Anthony Gean
التنسيق: Artigo
اللغة:Inglês
منشور في: Frontiers Research Foundation 2012
الموضوعات:
Genetics
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371589/
https://ncbi.nlm.nih.gov/pubmed/22701466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2012.00086
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