Variants in CPT1A, FADS1, and FADS2 are Associated with Higher Levels of Estimated Plasma and Erythrocyte Delta-5 Desaturases in Alaskan Eskimos

The delta-5 and delta-6 desaturases (D5D and D6D), encoded by fatty acid desaturase 1 (FADS1) and 2 (FADS2) genes, respectively, are rate-limiting enzymes in the metabolism of ω-3 and ω-6 fatty acids. The objective of this study was to identify genes influencing variation in estimated D5D and D6D ac...

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Autors principals: Voruganti, V. Saroja, Higgins, Paul B., Ebbesson, Sven O. E., Kennish, John, Göring, Harald H. H., Haack, Karin, Laston, Sandra, Drigalenko, Eugene, Wenger, Charlotte R., Harris, William S., Fabsitz, Richard R., Devereux, Richard B., MacCluer, Jean W., Curran, Joanne E., Carless, Melanie A., Johnson, Matthew P., Moses, Eric K., Blangero, John, Umans, Jason G., Howard, Barbara V., Cole, Shelley A., Comuzzie, Anthony Gean
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Research Foundation 2012
Matèries:
Genetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371589/
https://ncbi.nlm.nih.gov/pubmed/22701466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2012.00086
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