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Coordinated regulation of neuronal mRNA steady-state levels through developmentally controlled intron retention

Differentiated cells acquire unique structural and functional traits through coordinated expression of lineage-specific genes. An extensive battery of genes encoding components of the synaptic transmission machinery and specialized cytoskeletal proteins is activated during neurogenesis, but the unde...

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Bibliographic Details
Main Authors: Yap, Karen, Lim, Zhao Qin, Khandelia, Piyush, Friedman, Brad, Makeyev, Eugene V.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371409/
https://ncbi.nlm.nih.gov/pubmed/22661231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.188037.112
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