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Telomere end processing: unexpected complexity at the end game
Most human cells lack telomerase, the enzyme that elongates telomeres. The resulting telomere erosion eventually limits cell proliferation and tissue renewal, thereby impacting age-dependent pathologies. In this issue of Genes & Development, a technical tour-de-force by Chow and colleagues (pp....
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| Auteur principal: | |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Cold Spring Harbor Laboratory Press
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3371402/ https://ncbi.nlm.nih.gov/pubmed/22661225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.195339.112 |
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