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Characterization of an arachidonic acid-deficient (Fads1 knockout) mouse model

Arachidonic acid (20:4(Δ5,8,11,14), AA)-derived eicosanoids regulate inflammation and promote cancer development. Previous studies have targeted prostaglandin enzymes in an attempt to modulate AA metabolism. However, due to safety concerns surrounding the use of pharmaceutical agents designed to tar...

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Detalhes bibliográficos
Main Authors: Fan, Yang-Yi, Monk, Jennifer M., Hou, Tim Y., Callway, Evelyn, Vincent, Logan, Weeks, Brad, Yang, Peiying, Chapkin, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371240/
https://ncbi.nlm.nih.gov/pubmed/22534642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M024216
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