n–3 PUFAs Reduce T-Helper 17 Cell Differentiation by Decreasing Responsiveness to Interleukin-6 in Isolated Mouse Splenic CD4(+) T Cells(1)(2)(3)

Cluster of differentiation 4(+) (CD4(+)) effector T-cell subsets [e.g., T-helper (Th) 1 and Th17] are implicated in autoimmune and inflammatory disorders such as multiple sclerosis, psoriasis, and rheumatoid arthritis. Interleukin (IL)-6 is a pleiotropic cytokine that induces Th17 polarization via s...

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Detalhes bibliográficos
Main Authors: Allen, M. Jeannie, Fan, Yang-Yi, Monk, Jennifer M., Hou, Tim Y., Barhoumi, Rola, McMurray, David N., Chapkin, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Nutrition 2014
Assuntos:
Nutritional Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4093987/
https://ncbi.nlm.nih.gov/pubmed/24944284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3945/jn.114.194407
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