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Reciprocal effects of NNK and SLURP-1 on oncogene expression in target epithelial cells

AIMS: To elucidate how the nicotinic acetylcholine receptors expressed on bronchial and oral epithelial cells targeted by the tobacco nitrosamine (4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone) (NNK) facilitate carcinogenic transformation. MAIN METHODS: Since NNK-dependent transformation can be abo...

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Autors principals: Kalantari-Dehaghi, Mina, Bernard, Hans-Ulrich, Grando, Sergei A
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371149/
https://ncbi.nlm.nih.gov/pubmed/22369755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2012.02.004
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