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OVEREXPRESSION OF SLURP-1 AND -2 ALLEVIATES THE TUMORIGENIC ACTION OF TOBACCO-DERIVED NITROSAMINE ON IMMORTALIZED ORAL EPITHELIAL CELLS

Recent research has demonstrated that mucocutaneous epithelial cells express functional nicotinic acetylcholine receptors (nAChRs) and that tobacco-derived carcinogenic nitrosamines, such as 4-(methylnitrosamino)-1-(3–pyridyl)-1-butanone (NNK), and SLURP (secreted mammalian Ly-6/urokinase plasminoge...

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Detalhes bibliográficos
Main Authors: Arredondo, Juan, Chernyavsky, Alex I, Grando, Sergei A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2046218/
https://ncbi.nlm.nih.gov/pubmed/17643396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2007.06.026
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