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OVEREXPRESSION OF SLURP-1 AND -2 ALLEVIATES THE TUMORIGENIC ACTION OF TOBACCO-DERIVED NITROSAMINE ON IMMORTALIZED ORAL EPITHELIAL CELLS
Recent research has demonstrated that mucocutaneous epithelial cells express functional nicotinic acetylcholine receptors (nAChRs) and that tobacco-derived carcinogenic nitrosamines, such as 4-(methylnitrosamino)-1-(3–pyridyl)-1-butanone (NNK), and SLURP (secreted mammalian Ly-6/urokinase plasminoge...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2046218/ https://ncbi.nlm.nih.gov/pubmed/17643396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2007.06.026 |
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