Chronic immune activation is a distinguishing feature of liver and PBMC gene signatures from HCV/HIV coinfected patients and may contribute to hepatic fibrogenesis

Hepatitis C virus/human immunodeficiency virus (HCV/HIV) coinfected patients demonstrate accelerated progression to severe liver injury in comparison to HCV monoinfected patients, although the underlying mechanisms are unclear owing to infection of separate tissue compartments with two distinct vira...

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Detalhes bibliográficos
Main Authors: Rasmussen, Angela L., Wang, I-Ming, Shuhart, Margaret C., Proll, Sean C., He, Yudong, Cristescu, Razvan, Roberts, Chris, Carter, Victoria S., Williams, Christopher M., Diamond, Deborah L., Bryan, Janine T., Ulrich, Roger, Korth, Marcus J., Thomassen, Lisa V., Katze, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3371131/
https://ncbi.nlm.nih.gov/pubmed/22608059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2012.04.011
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